Our products are nothing but pure. Produced locally, our dietary supplements are formulated with premium raw ingredients and are scientifically tested to ensure that each ingredient and final product meets our quality standards.
At Pure Encapsulations, we manufacture hypoallergenic, research-based dietary supplements that are designed to deliver predictable and desired results. We are committed to sourcing pure, premium ingredients and working with experienced healthcare professionals to create safe and effective dietary supplements to help you achieve optimal health.
Based on your healthcare practitioner’s medical guidance, we help provide you with the tools and dietary supplements you need to achieve your health and wellness goals. To purchase our products, you must obtain a fulfillment code from your practitioner.
We source premium raw materials from trusted industry leaders, including the finest suppliers from the U.S., France, Japan, Switzerland, Germany and Italy. All ingredients are tested for purity and potency by independent certified laboratories. Ingredient suppliers must meet rigorous testing and quality criteria to qualify as a Pure Encapsulations supplier
Phytosterol, berberine and flavonoid-rich bergamot extract for healthy cholesterol, triglyceride, and glucose metabolism*
- Supports phytosterol intake and overall cardiovascular health*
- Promotes healthy cholesterol metabolism*
- Improved, soy-free formula
- Made with vegan ingredients
CholestePure Plus II* Plus provides a unique blend of phytosterols, berberine and clinically studied bergamot extract to promote healthy lipid metabolism and overall cardiometabolic health.*
CholestePure Plus II* provides a unique blend of phytosterols, berberine and clinically studied bergamot extract to promote healthy lipid metabolism and overall cardiometabolic health*
Phytosterols are structural homologs of cholesterol that occur naturally in many plant foods. Over 30 years of research and 40 clinical trials suggest that phytosterols provide significant support for healthy lipid profiles. Well-established benefits of phytosterols on lipid balance stem primarily from competition with cholesterol for occupancy in micelles, particles that carry cholesterol across the intestinal epithelium into the systemic circulation.
Through this mechanism, phytosterols promote excretion of cholesterol in the form of bile acids. Research indicates that the pine-derived phytosterols offered in this formula are comparable to phytosterols from other sources. Bergamot is a citrus fruit containing two newly discovered derivatives of the flavonoids hesperidin and naringenin. These compounds are naturally conjugated to a moiety known as hydroxymethylglutarate (HMG).
In the liver, this unique molecule binds and modulates an enzyme known as HMG CoA reductase, which plays a central role in lipid biosynthesis. These unique compounds also target enzymes, transcription factors and genes involved in lipid metabolism. In a study involving 192 volunteers, bergamot juice maintained healthy cholesterol and triglyceride levels in the normal range over a 30-day period. In a separate study of 80 subjects, 150 mg of flavonoids from Bergavit® 40 bergamot extract supported healthy lipid, triglyceride and glucose profiles over a 6-month period.
Berberine supports cardiometabolic health through a variety of mechanisms, including support for glucose and lipid metabolism, antioxidant defenses, and cytokine production. In a randomized, placebo-controlled trial involving 116 subjects, berberine provided statistically significant support for glucose, lipid and triglyceride metabolism. It also helps maintain endothelial function by promoting healthy vascular cell adhesion molecule-1 (VCAM-1) expression and healthy iNOS activity.*